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IKKγ polyclonal antibody

货号: BS6772

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6772

Product Name :IKKγ polyclonal antibody

Swiss-Prot :Q9Y6K9

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:2000 IHC/IF: 1:50~1:200

Background :IKKα appears to be critical for NFkB activation in response to proinflammatory cytokines. Phosphorylation of IkB by IKKα is stimulated by the NFkB inducing kinase (NIK), which itself is a central regulator for NFkB activation in response to TNF and IL-1. The functional IKK complex contains three subunits, IKKα, IKKβ and IKKγ (also designated NEMO), and each appear to make essential contributions to IkB phosphorylation.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IKKγ polyclonal antibody detects endogenous levels of IKKγ protein.

BiowMW :~ 48 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :NF-kB Signaling,STING Signaling,Inhibition of Apoptosis,Toll-like Receptor signaling,

Alternative Name :NF-kappa-B essential modulator; NEMO; FIP-3; IkB kinase-associated protein 1; IKKAP1; Inhibitor of nuclear factor kappa-B kinase subunit gamma; I-kappa-B kinase subunit gamma; IKK-gamma; IKKG; IkB kinase subunit gamma; NF-kappa-B essential modifier; IKBKG; FIP3; NEMO; IKK-γ

Immunogen :Recombinant full length Human IKKγ.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of various cell lines, using IKKγ antibody.

Immunohistochemistry (IHC) analysis of IKKγ polyclonal antibody in paraffin-embedded Rat Testis tissue.

Immunofluorescence analysis of MCF-7 cells, using IKKγ polyclonal antibody

METTL3/METTL14 transactivation and m6A-dependent TGF-β1 translation in activated Kupffer cells

JournalCellular and Molecular Gastroenterology and Hepatology

ApplicationWB

IF7.076

SpeciesRat

PMID33992834