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XPA polyclonal antibody

货号: BS6766

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6766

Product Name :XPA polyclonal antibody

Swiss-Prot :P23025

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB IF

Application_all :WB 1:500 - 1:2000 IF 1:50 - 1:100

Background :The XPA gene encodes a 31 kDa zinc metalloprotein that preferentially binds to DNA damaged by UV radiation and chemical carcinogens and is required for the incision step during nucleotide excision repair. The XPB and XPD genes encode DNA helicases involved in several DNA metabolic pathways, including DNA repair and transcription, and the XPG gene product is an endonuclease that cuts on the 3' side of a DNA lesion during nucleotide excision repair. Molecular defects in the XP variant (XPV) group maintain normal excision repair, yet they result in a substantial reduction in the ability to synthesize intact daughter DNA strands during DNA replication following DNA damage.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :XPA polyclonal antibody detects endogenous levels of XPA protein.

BiowMW :~ 37 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :DNA repair protein complementing XP-A cells; Xeroderma pigmentosum group A-complementing protein; XPA; XPAC

Immunogen :Recombinant full length Human XPA.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of XPA polyclonal antibody

Western blot analysis of extracts from normal (control) and XPA knockout (KO) HeLa cells, using XPA antibody.

免疫沉淀（IP）

免疫组织化学（IHC）