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IL-1 beta polyclonal antibody

货号: BS67482

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS67482

Product Name :IL-1 beta polyclonal antibody

Swiss-Prot :P01584

Host :Rabbit

Reactivity :Human, Mouse, Monkey

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Interleukin-1β (IL-1β), one of the major caspase-1 targets, is a multifunctional cytokine that is involved in a host of immune and proinflammatory responses . It is produced primarily by activated monocytes and macrophages. It signals through various adaptor proteins and kinases that lead to activation of numerous downstream targets . Human IL-1β is synthesized as a 31 kDa precursor. To gain activity, the precursor must be cleaved by caspase-1 between Asp116 and Ala117 to yield a 17 kDa mature form . Detection of the 17 kDa mature form of IL-1β is a good indicator of caspase-1 activity.

Product :Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of IL-1 beta protein.

BiowMW :~ 38 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :IL1F2; Interleukin-1 beta; IL-1 beta; Catabolin

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human IL-1 beta. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of IL-1 beta expression in Jurkat (A), Myla2059 (B), Raw264.7 (C) whole cell lysates.

免疫沉淀（IP）