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VAP-A polyclonal antibody

货号: BS67356

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS67356

Product Name :VAP-A polyclonal antibody

Swiss-Prot :Q9P0L0

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC

Application_all :WB (1/500 - 1/2000), IHC (1/50 - 1/200)

Background :Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites.The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface.With OSBPL3, may regulate ER morphology.May play a role in vesicle trafficking.

Product :Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of VAP-A protein

BiowMW :~ 27 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :VAP33; Vesicle-associated membrane protein-associated protein A; VAMP-A; VAMP-associated protein A; VAP-A; 33 kDa VAMP-associated protein; VAP-33

Immunogen :Recombinant fusion protein of human VAP-A. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of VAP-A expression in B cell (A), mouse heart (B), mouse pancreas (C) whole cell lysates.

Immunohistochemical analysis of VAP-A staining in human stomach formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.