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Histone H4 (MonoMethyl-R17) polyclonal antibody

货号: BS67183

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS67183

Product Name :Histone H4 (MonoMethyl-R17) polyclonal antibody

Swiss-Prot :P62805

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Product :Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 144% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of Histone H4 with a Mono-methylation site at R17 protein.

BiowMW :~ 12 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :H4/A; H4FA; H4/I; H4FI; H4/G; H4FG; H4/B; H4FB; H4/J; H4FJ; H4/C; H4FC; H4/H; H4FH; H4/M; H4FM; H4/E; H4FE; H4/D; H4FD; H4/K; H4FK; H4/N; H4F2; H4FN; HIST2H4; H4/O; H4FO; Histone H4

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Histone H4 with a Mono-methylation site at R17. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Methylated

Western blot analysis of Histone H4 (MonoMethyl-R17) expression in HEK293T (A), HCT116 (B) whole cell lysates.