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MADD polyclonal antibody

货号: BS67010

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS67010

Product Name :MADD polyclonal antibody

Swiss-Prot :Q8WXG6

Host :Rabbit

Reactivity :Human, Rat

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Guanyl-nucleotide exchange factor that regulates small GTPases of the Rab family (PubMed:20937701, PubMed:18559336).Converts GDP-bound inactive form of RAB27A and RAB27B to the GTP-bound active forms (PubMed:20937701, PubMed:18559336).Converts GDP-bound inactive form of RAB3A, RAB3C and RAB3D to the GTP-bound active forms, GTPases involved in synaptic vesicle exocytosis and vesicle secretion (By similarity).Plays a role in synaptic vesicle formation and in vesicle trafficking at the neuromuscular junction (By similarity).Involved in up-regulating a post-docking step of synaptic exocytosis in central synapses (By similarity).

Product :Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of MADD protein.

BiowMW :~ 200 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :DENN; IG20; KIAA0358; MAP kinase-activating death domain protein; Differentially expressed in normal and neoplastic cells; Insulinoma glucagonoma clone 20; Rab3 GDP/GTP exchange factor

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MADD. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of MADD expression in PC12 (A) whole cell lysates.