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NPPA polyclonal antibody

货号: BS6680

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6680

Product Name :NPPA polyclonal antibody

Swiss-Prot :P01160

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB

Application_all :WB 1:500 - 1:2000

Background :Natriuretic peptides comprise a family of 3 structurally related molecules: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP). ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. These peptides possess potent natriuretic, diuretic, and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control. ANP, BNP, and CNP are highly homologous within the 17-residue ring structure formed by an intramolecular disulfide linkage. The genes which encode for ANP and BNP map to human chromosome 1p36.2. The gene which encodes for CNP maps to human chromosome 2q24-qter.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :NPPA polyclonal antibody detects endogenous levels of NPPA protein.

BiowMW :~ 16 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ANF; ANF; ANP; ATFB6; Atrial natriuretic factor; Atrial natriuretic peptide; Atriopeptin; Cardionatrin; CDD-ANF; CDP; Natriuretic peptide A; Natriuretic peptide precursor A; Natriuretic peptides A; NPPA; PND; Prepronatriodilatin; Pronatriodilatin;

Immunogen :Recombinant full length Human NPPA.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of PC-3 cell lines, using NPPA antibody.

Small molecule QF84139 ameliorates cardiac hypertrophy via activating the AMPK signaling pathway

JournalActa Pharmacologica Sinica

ApplicationIF,WB

IF6.15

SpeciesMouse

PMID33967278