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IL-10 (3-8) monoclonal antibody

货号: BS66505

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS66505

Product Name :IL-10 (3-8) monoclonal antibody

Swiss-Prot :P22301

Host :Mouse

Reactivity :Human,Rat,Mouse

Applications :WB

Application_all :WB: 1:1000~1:2000

Background :The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IL1β polyclonal antibody detects endogenous levels of IL1β protein.

BiowMW :~ 43, 35, 17 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :IL-1;IL1-BETA;IL1F2;IL1 beta;IL1B

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human IL1β.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of IL1β expression in Raw264.7 (A), mouse spleen (B), rat spleen (C), rat thymus (D), mouse thymus (E), Jurkat (F), THP1 (G) whole cell lysates.