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GCSH polyclonal antibody

货号: BS66211

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS66211

Product Name :GCSH polyclonal antibody

Swiss-Prot :P23434

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IF/ICC

Application_all :WB: 1:500~1:2000 IF/ICC: 1:50~1:200

Background :Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :GCSH pAb detects endogenous levels of GCSH protein.

BiowMW :~ 19 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Glycine cleavage system H protein mitochondrial; Lipoic acid-containing protein

Immunogen :Recombinant fusion protein of human GCSH.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of GCSH expression in HeLa (A), mouse kidney (B), rat liver (C) whole cell lysates.

Immunofluorescent analysis of GCSH staining in L929 cells.

免疫沉淀（IP）

免疫组织化学（IHC）