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GLS polyclonal antibody

货号: BS66209

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS66209

Product Name :GLS polyclonal antibody

Swiss-Prot :O94925

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, IF/ICC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF/ICC: 1:50~1:200

Background :Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity. Isoform 1 and isoform 3 are activated by phosphate. Inhibited by BPTES. BPTES binds between subunits and favors dissociation of the tetramer into dimers.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :GLS pAb detects endogenous levels of GLS protein.

BiowMW :~ 73 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :GLS1; KIAA0838; Glutaminase kidney isoform mitochondrial; GLS; K-glutaminase; L-glutamine amidohydrolase

Immunogen :Recombinant full length protein of human GLS

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of GLS expression in SW620 (A), mouse lung (B) whole cell lysates.

mmunohistochemical analysis of GLS staining in human brain formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of GLS staining in NIH3T3 cells.

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