Product Name :CHRDL1 polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB: 1:500-1:1000
IHC-P: 1:50-1:100
Background :Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation (By similarity).
May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :CHRDL1 polyclonal antibody detects endogenous levels of CHRDL1 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :chordin-like 1; CHL; MGC1; MGCN; VOPT; NRLN1; dA141H5.1
Immunogen :Synthetic peptide of human CHRDL1
