产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

Acetyl-alpha Tubulin -K40 polyclonal antibody

货号: BS66185

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS66185

Product Name :Acetyl-alpha Tubulin -K40 polyclonal antibody

Swiss-Prot :Q71U36

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB IF/ICC

Application_all :WB: 1:500~1:1000 IF/ICC: 1:50~1:200

Background :Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blot studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, intellectual disability, and early-onset epilepsy caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Acetyl-alpha Tubulin -K40 polyclonal antibody detects endogenous levels of alpha Tubulin -K40 protein only when acetylated at Lys40.

BiowMW :~ 50 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :LIS3; TUBA3; B-ALPHA-1; Acetyl-alpha Tubulin -K40

Immunogen :A synthetic acetylated peptide around K40 of human alpha Tubulin.

Conjugate :Unconjugated

Modification :Acetylated

Western blot analysis of lysates from HeLa cells, using Acetyl-alpha Tubulin -K40 pAb at 1:500 dilution.

Western blot analysis of various lysates, using Acetyl-alpha Tubulin -K40 pAb at 1:500 dilution.

Immunofluorescence analysis of paraffin-embedded rat testis using Acetyl-alpha Tubulin -K40 pAb at dilution of 1:50 (40x lens).

免疫沉淀（IP）