Product Name :CEMP1 polyclonal antibody
Applications :ELISA IHC IF ICC
Application_all :ELISA: 1:5000-1:10000
IHC: 1:100-1:500
IF: 1:100-1:500
ICC: 1:100-1:500
Background :A mineralized connective tissue known as cementum covers the root surfaces of teeth and is required for maturation of periodontal tissue. CEMP1 (cementum protein 1), also designated CP23 or cementoblastoma-derived protein 1, is a 247 amino acid nuclear and cytoplasmic protein that is thought to regulate cementoblast behavior. Expressed specifically in periodontal ligament and cementum, CEMP1 may play a role in differentiation and mineralization of non-osteogenic cells. The gene encoding CEMP1 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity :CEMP1 polyclonal antibody detects endogenous levels of CEMP1 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Cementoblastoma-derived protein 1; Cementum protein 1; Cementum protein 23; CEMP1; CEMP1_HUMAN; CP-23; CP23
Immunogen :KLH conjugated synthetic peptide derived from human CEMP1: 151-247/247
Modification :Unmodification
