产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

CCBR1 polyclonal antibody

货号: BS66108

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS66108

Product Name :CCBR1 polyclonal antibody

Swiss-Prot :Q9UPY5

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:500~1:2000

Background :This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CCBR1 polyclonal antibody detects endogenous levels of CCBR1 protein.

BiowMW :~ 55 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Amino acid transport system xc xCT antibody; Amino acid transport system xc- antibody Calcium channel blocker resistance protein CCBR1; Calcium channel blocker resistance protein CCBR1 antibody; CCBR1; Cysteine/glutamate transporter antibody; cystine/glutamate transporter; SLC7A11; Solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11; solute carrier family 7; Solute carrier family 7 member 11; Solute carrier family 7, (cationic amino acid transporter, y+ system) member 11; xCT; XCT_HUMAN

Immunogen :KLH conjugated synthetic peptide derived from human xCT/CCBR1: 201-300/501 <Extracellular>

Conjugate :Unconjugated

Modification :Unmodification

Primary: Anti-CCBR1 at 1/1000 dilution

Co-exposure to environmentally relevant concentrations of cadmium and polystyrene nanoplastics induced oxidative stress, ferroptosis and excessive mitophagy in mice kidney

JournalENVIRONMENTAL POLLUTION

ApplicationWB,IHC

IF8.9

SpeciesMouse

PMID37270049
A multifunctional bimetallic nanoplatform for enhancing radiotherapy via oxidative damage and ferroptosis of cervical cancer

JournalSEPARATION AND PURIFICATION TECHNOLOGY

ApplicationWB

IF8.6

SpeciesMouse

PMID