Product Name :KAT2B Polyclonal Antibody
Reactivity :Human,Mouse,Rat,Chicken,Dog,Pig,Horse,
Application_all :Flow-Cyt=1ug/Test
Background :Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes.
Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Purification&Purity :affinity purified by Protein A
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :KAT2B Polyclonal Antibody detects endogenous levels of KAT2B protein.
Note :For research use only, not for use in diagnostic procedure.
Pathway :Nuclear Receptor Signaling,Epigenetic Writers and Erasers of Histone H3,Epigenetic Writers and Erasers of Histones H2A H2B and H4,
Alternative Name :GCN5; PCAF; CAF; CREBBP associated factor; GCN5; GCN5L; GCN5L1 antibody Histone acetylase PCAF; Histone acetyltransferase KAT2B; Histone acetyltransferase PCAF; K(lysine) acetyltransferase 2B; KAT2B; KAT2B_HUMAN; Lysine acetyltransferase 2B; P antibody P/CAF; p300/CBP associated factor; P300/CBP-associated factor; Pcaf.
Immunogen :KLH conjugated synthetic peptide derived from human KAT2B:451-550/832
Modification :Unmodification
