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CYP2R1 Polyclonal Antibody

货号: BS65875

价格：￥ ——

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS65875

Product Name :CYP2R1 Polyclonal Antibody

Swiss-Prot :Q6VVX0

Host :Rabbit

Reactivity :Human,Mouse,Rat,Dog,Pig,Horse,Rabbit,

Applications :WB,

Application_all :WB=1:500-2000

Background :CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are mono-oxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. Defects in CYP2R1 are a cause of 25-hydroxyvitamin D(3) deficiency, also known as pseudovitamin D(3) deficiency rickets due to 25-hydroxylase deficiency. First described in patients who had rickets at a young age despite a history of adequate vitamin D intake. The patients sera had low calcium concentrations, low phosphate concentrations, elevated alkaline phosphatase activity and low levels of 25-hydroxyvitamin D.

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :affinity purified by Protein A

Storage&Stability :Store at 4°C short term. Aliquot and store at -48°C long term. Avoid freeze-thaw cycles.

Specificity :CYP2R1 Polyclonal Antibody detects endogenous levels of CYP2R1 protein.

BiowMW :~53kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Cytochrome P450 2R1; Cytochrome P450 family 2 R1; Cytochrome P450 family 2 subfamily R polypeptide 1; EC 1.14.13.15; MGC4663; Vitamin D 25 hydroxylase.

Immunogen :KLH conjugated synthetic peptide derived from human CYP2R1:251-350/501

Conjugate :Unconjugated

Modification :Unmodification

Primary: Anti-CYP2R1 at 1/1000 dilution

Primary: Anti- CYP2R1 at 1/1000 dilution