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VP16 tagPolyclonal Antibody

货号: BS65868

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS65868

Product Name :VP16 tagPolyclonal Antibody

Swiss-Prot :P04486

Host :Rabbit

Reactivity :Human herpesvirus 1

Applications :WB,

Application_all :WB=1:500-2000

Background :HSV evades the immune system through interference with MHC class I antigen presentation on the cell surface, by blocking TAP or the transporter associated with antigen processing induced by the secretion of ICP-47 by HSV. In the host cell, TAP transports digested viral antigen epitope peptides from the cytosol to the endoplasmic reticulum, allowing these epitopes to be combined with MHC class I molecules and presented on the surface of the cell. Viral epitope presentation with MHC class I is a requirement for activation of cytotoxic T-lymphocytes (CTLs), the major effectors of the cell-mediated immune response against virally-infected cells. ICP-47 prevents initiation of a CTL-response against HSV, allowing the virus to survive for a protracted period in the host.

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :affinity purified by Protein A

Storage&Stability :Store at 4°C short term. Aliquot and store at -41°C long term. Avoid freeze-thaw cycles.

Specificity :VP16 tag Polyclonal Antibody detects endogenous levels of VP16 tag protein.

BiowMW :~51 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :VP16_HHV1F;UL48; Tegument protein VP16; Alpha trans-inducing protein; Alpha-TIF; ICP25; Vmw65

Immunogen :KLH conjugated synthetic peptide derived from HSV-1 VP16:391-490/490aa

Conjugate :Unconjugated

Modification :Unmodification

Primary: Anti-VP16 tag at 1/1000 dilution

Antiviral Activity of Paulownia tomentosa against Enterovirus 71 of Hand, Foot, and Mouth Disease

JournalBiological & Pharmaceutical Bulletin

ApplicationWB

IF1.863

SpeciesMonkey

PMID25744451