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CD34 Polyclonal Antibody

货号: BS65854

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS65854

Product Name :CD34 Polyclonal Antibody

Swiss-Prot :Q64314

Host :Rabbit

Reactivity :Human,Mouse,Rat,

Applications :WB,

Application_all :WB=1:500-2000

Background :The highly glycosylated 75-120 kD antigen CD34 is possibly an adhesion molecule with a putative role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is thought to have a role in presenting carbohydrate ligands to selectins. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C, suggesting a putative role in signal transduction. Two isoforms of CD34 have been reported to be generated by alternative splicing. CD34 is highly expressed on hematopoietic progenitors, as well as on endothelial cells, brain, and testis. Staining for CD34 has been used to measure angiogenesis, which reportedly predicts tumor recurrence.

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :affinity purified by Protein A

Storage&Stability :Store at 4°C short term. Aliquot and store at -27°C long term. Avoid freeze-thaw cycles.

Specificity :CD34 Polyclonal Antibody detects endogenous levels of CD34 protein.

BiowMW :~120 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CD34 antigen; CD34 molecule; Cluster designation 34; Hematopoietic progenitor cell antigen CD34; HPCA1; CD34_HUMAN; Hematopoietic Stem Cell Marker; Endothelial Markers; Tumor biomarkers.

Immunogen :KLH conjugated synthetic peptide derived from human CD34:201-300/382<Extracellular>

Conjugate :Unconjugated

Modification :Unmodification

Primary: Anti-CD34 at 1/1000 dilution