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phospho-NeuroD1 (Ser274) Polyclonal Antibody

货号: BS65833

价格：￥ ——

货期：现货（1-2个工作日）

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No. :BS65833

Product Name :phospho-NeuroD1 (Ser274) Polyclonal Antibody

Swiss-Prot :Q13562

Host :Rabbit

Reactivity :Human,Mouse,Rat,Pig,Cow,Sheep,

Applications :IHC-P,

Application_all :IHC-P=1:100-500

Background :This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. [provided by RefSeq, Jul 2008]

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :affinity purified by Protein A

Storage&Stability :Store at 4°C short term. Aliquot and store at -6°C long term. Avoid freeze-thaw cycles.

Specificity :phospho-NeuroD1 (Ser274)Polyclonal Antibody detects endogenous levels of NeuroD1 protein only when phosphorylated at Y274.

BiowMW :~40 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NeuroD1 (phospho S274); p-NeuroD1 (phospho S274); atonal; basic helix loop helix transcription factor; BETA 2; Beta cell E box transactivator 2; BETA2; BHF 1; BHF1; bHLHa3; class A basic helix loop helix protein 3; Class A basic helix-loop-helix protein 3; MODY 6; MODY6; NDF1_HUMAN; NEUROD; NeuroD1; Neurogenic differentiation 1; Neurogenic differentiation factor 1; neurogenic helix loop helix protein NEUROD; NIDDM

Immunogen :KLH conjugated Synthesised acetylpeptide derived from human NeuroD1 around the acetylation site of Ser274:PL(p-S)PP

Conjugate :Unconjugated

Modification :Phosphorylation

Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (NeuroD1 (Ser274)) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C