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LPHN1 Polyclonal Antibody

货号: BS65810

价格：￥ ——

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS65810

Product Name :LPHN1 Polyclonal Antibody

Swiss-Prot :O94910

Host :Rabbit

Reactivity :Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,

Applications :IHC-P,

Application_all :IHC-P=1:100-500

Background :This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :affinity purified by Protein A

Storage&Stability :Store at 4°C short term. Aliquot and store at -17°C long term. Avoid freeze-thaw cycles.

Specificity :LPHN1 Polyclonal Antibody detects endogenous levels of LPHN1 protein.

BiowMW :~160 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Calcium independent alpha latrotoxin receptor 1; Calcium-independent alpha-latrotoxin receptor 1; CIRL-1; CIRL1; CL1; CLIBA; G protein-coupled receptor for alpha-Latrotoxin; KIAA0821; Latrophilin 1; Latrophilin-1; Latrophilin1; LEC2; Lectomedin 2; Lectomedin-2; LPHN 1; LPHN1; LPHN1_HUMAN.

Immunogen :KLH conjugated synthetic peptide derived from human LPHN1:201-300/1474<Extracellular>

Conjugate :Unconjugated

Modification :Unmodification

Paraformaldehyde-fixed, paraffin embedded (rat kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (LPHN1) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C