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ERG/KCNH2 Polyclonal Antibody

货号: BS65805

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS65805

Product Name :ERG/KCNH2 Polyclonal Antibody

Swiss-Prot :Q12809

Host :Rabbit

Reactivity :Human,Mouse,Rat,Dog,Pig,Horse,Rabbit,

Applications :ICC,

Application_all :ICC=1:100-500

Background :The potassium voltage gated channel, subfamily H (eag related), member 2 (KCNH2) gene encodes a voltage-gated potassium channel which has an important role in cardiac action potential repolarization in the mammalian heart. Mutations in KCNH2 have been shown to cause chromosome 7-linked congenital long QT syndrome, a disorder associated with delayed cardiac repolarization, prolonged electrocardiographic QT intervals, and the development of ventricular arrhythmias. KCNH2 channels are an important target for many drugs, and have emerged as a significant type of cardiac ion channel.Highly expressed in heart and brain.

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :affinity purified by Protein A

Storage&Stability :Store at 4°C short term. Aliquot and store at -22°C long term. Avoid freeze-thaw cycles.

Specificity :ERG/KCNH2 Polyclonal Antibody detects endogenous levels of ERG/KCNH2 protein.

BiowMW :~127 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ERG; ERG1; H ERG; HERG 1; HERG; HERG1; LQT 2; LQT2; Potassium channel HERG; SQT1; Voltagegated potassium channel, subfamily H, member 2; KCNH2_HUMAN.

Immunogen :KLH conjugated synthetic peptide derived from human HERG:1001-1159/1159<Cytoplasmic>

Conjugate :Unconjugated

Modification :Unmodification

Tissue/cell: MCF-7 cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum, C-0005) at 37°C for 20 min; Antibody incubation with (ERG/KCNH2) Polyclonal Antibody, Unconjugated 1:100, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (5ug/ml, blue, C-0033) was used to stain the cell nuclei.