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VEGF-C Polyclonal Antibody

货号: BS65789

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS65789

Product Name :VEGF-C Polyclonal Antibody

Swiss-Prot :P97953

Host :Rabbit

Reactivity :Human,Mouse,Rat,

Applications :WB,

Application_all :WB=1:500-2000

Background :Vascular endothelial growth factors (VEGFs), also known as vasculotropins, are a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGFs stimulate the proliferation of endothelial cells, induce angiogenesis, promote cell migration, increase vascular permeability, and inhibit apoptosis. The mitogenic activity of VEGFs appears to be mediated by specific VEGF receptors. The target cell specificity of VEGF is restricted to vascular endothelial cells. Vascular Endothelial Growth Factor C (VEGFC) is a member of the VEGF subfamily of PDGF-related growth factors. It is the ligand for Flt4 (VEGFR3) and KDR (VEGFR2). VEGFC binds Flt4 and induces tyrosine autophosphorylation of VEGFR3 and VEGFR2. VEGFC also stimulates the migration of bovine capillary endothelial cells in collagen gel. It is a specific growth factor for the lymphatic vascular system and mediates lymphangiogenesis. VEGFC is abundantly expressed in heart and skeletal muscle. Other tissues such as lung and kidney also express VEGFC.

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :affinity purified by Protein A

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :VEGF-C Polyclonal Antibody detects endogenous levels of VEGF-C protein.

BiowMW :46 kD

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Vascuoar endothelial growth factor-C; AW228853; Flt4 ligand; Flt4-L; VEGF2; VEGFC; VRP; VEGFC_HUMAN.聽聽

Immunogen :KLH conjugated synthetic peptide derived from human VEGF-C:321-415/415

Conjugate :Unconjugated

Modification :Unmodification

Anti-VEGF-C at 1/1000 dilution

Differential expression of vascular endothelial growth factor‑A, ‑C and ‑D for the diagnosis and prognosis of cancer patients with malignant effusions

JournalOncology Letters

ApplicationICC

IF2.311

SpeciesHuman

PMID26622551