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PAFR/PAF Receptor Polyclonal Antibody

货号: BS65779

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS65779

Product Name :PAFR/PAF Receptor Polyclonal Antibody

Swiss-Prot :P25105

Host :Rabbit

Reactivity :Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,

Applications :WB,IHC-P,

Application_all :WB=1:500-2000，IHC-P=1:100-500

Background :The PAF receptor binds platelet-activating factor (PAF) and is thought to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system. PAF is a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. It has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes.The PAF receptor is induced by granulocyte macrophage colony-stimulating factor (GM-CSF), interleukin-5 and n-butyrate. A diverse range of compounds act as PAF receptor antagonists; these may be useful pharmacologically.

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :affinity purified by Protein A

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :PAFR/PAF Receptor Polyclonal Antibody detects endogenous levels of PAFR/PAF Receptor protein.

BiowMW :38kD

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Platelet-activating factor receptor; PAF receptor; Ptafr; OTTHUMP00000004041; OTTMUSP00000010350; PAF R; PAF-R; PAFR; Platelet activating factor receptor; Platelet-activating factor receptor; PTAFR; PTAFR_HUMAN; RP23-470B20.1.聽聽

Immunogen :KLH conjugated synthetic peptide derived from human PAFR:231-342/342

Conjugate :Unconjugated

Modification :Unmodification

Primary: Anti-PTAFR at 1:200 dilution;

Primary: Anti- RAFR/PAF at 1/300 dilution

Tissue/cell: rat heart tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-PTAFR Polyclonal Antibody, Unconjugated 1:200, overnight at 4°C,