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ERO1LB Polyclonal Antibody

货号: BS65778

价格：￥ ——

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS65778

Product Name :ERO1LB Polyclonal Antibody

Swiss-Prot :Q86YB8

Host :Rabbit

Reactivity :Human,Mouse,Rat,Rabbit,Guinea Pig,

Applications :WB,

Application_all :WB=1:500-2000

Background :Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly P4HB/PDI isomerase through a direct disulfide exchange. Does not act as a direct oxidant of folding substrate, but relies on P4HB/PDI to transfer oxidizing equivalent. Associates with ERP44 but not with GRP54, demonstrating that it does not oxidize all PDI related proteins and can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. Acts independently of glutathione. May be responsible for a significant proportion of reactive oxygen species (ROS) in the being a source of oxidative stress. Required for the folding of cell, thereby being a source of oxidative stress.

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :affinity purified by Protein A

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ERO1LB Polyclonal Antibody detects endogenous levels of ERO1LB protein.

BiowMW :50 kD

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Endoplasmic oxidoreductin-1-like protein B; ERO1-L-beta; ERO1B_HUMAN; ERO1-like protein beta; Oxidoreductin-1-L-beta.

Immunogen :KLH conjugated synthetic peptide derived from human ERO1LB:1-100/467

Conjugate :Unconjugated

Modification :Unmodification

Primary: Anti-ERO1LB at 1/300 dilution

Primary: Anti- ERO1LB at 1/1000 dilution