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Glucocorticoid Receptor Polyclonal Antibody

货号: BS65758

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS65758

Product Name :Glucocorticoid Receptor Polyclonal Antibody

Swiss-Prot :P04150

Host :Rabbit

Reactivity :Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Sheep,

Applications :WB,

Application_all :WB=1:500-2000

Background :Steroid receptors are ligand-dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Glucocorticoids are a family of steroids necessary for the regulation of energy metabolism and the immune and inflammatory responses. These compounds exert their effect through their interaction with the glucocoticoid receptor (GR) and that complex's subsequent association with DNA. All normal mammalian tissues examined to date have been shown to contain glucocorticoid receptor.

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :affinity purified by Protein A

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Glucocorticoid Receptor Polyclonal Antibody detects endogenous levels of Glucocorticoid Receptor protein.

BiowMW :87 kD

Note :For research use only, not for use in diagnostic procedure.

Pathway :Nuclear Receptor Signaling,Nuclear Receptor Signaling,

Alternative Name :Glucocorticoid Receptor beta; GCCR; GCR; GCR_HUMAN; glucocorticoid nuclear receptor variant 1; Glucocorticoid receptor beta isoform; GR; GRL; nr3c1; Nuclear receptor subfamily 3 group C member 1.聽聽

Immunogen :KLH conjugated synthetic peptide derived from human Glucocorticoid Receptor beta:51-150/777

Conjugate :Unconjugated

Modification :Unmodification

Primary: Anti-Glucocorticoid Receptor at 1/1000 dilution

Chronic dexamethasone treatment results in hippocampal neurons injury due to activate NLRP1 inflammasome in vitro

JournalInternational Immunopharmacology

ApplicationIF,WB

IF3.943

SpeciesRat

PMID28605710