Product Name :AP2 alpha + beta Polyclonal Antibody
Reactivity :Human,Mouse,Rat,Chicken,Dog,Pig,Horse,Rabbit,Sheep,
Application_all :Flow-Cyt=1ug/test
Background :The AP2 proteins are normally expressed in ectodermally derived vertebrate tissues where they are necessary for normal growth and development. The factors have also been implicated in the control of cell proliferation, viral transformation, and oncogenesis. AP2 seems to play in important role in human breast cancer. AP2 alpha is the only AP2 protein required for early morphogenesis of the lens vesicle. AP2 beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.
Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Purification&Purity :affinity purified by Protein A
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :AP2 alpha + beta Polyclonal Antibody detects endogenous levels of AP2 alpha + beta protein.
Note :For research use only, not for use in diagnostic procedure.
Pathway :Vesicle Trafficking presynaptic signaling,
Alternative Name :Activating enhancer binding protein 2 alpha; Activating enhancer binding protein 2 beta; AP2TF; TFAP2; TFAP2A; TFAP2B; Transcription factor AP2 alpha; Transcription factor AP2 beta; AP2A_HUMAN; AP2B_HUMAN.
Immunogen :KLH conjugated synthetic peptide derived from human AP2 alpha + beta:201-300/437
Modification :Unmodification
