Product Name :KCTD7 Polyclonal Antibody
Reactivity :Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,
Application_all :Flow-Cyt=1ug/test
Background :Epilepsy affects about 0.5% of the world’s population and has a large genetic component. Epilepsy results from an electrical hyperexcitability in the central nervous system. Potassium channels are important regulators of electrical signaling, determining the firing properties and responsiveness of a variety of neurons. Benign familial neonatal convulsions (BFNC), an autosomal dominant epilepsy of infancy, has been shown to be caused by mutations in the KCNQ2 or the KCNQ3 potassium channel genes. KCNQ2 and KCNQ3 are voltage-gated potassium channel proteins with six putative transmembrane domains. Both proteins display a broad distribution within the brain, with expression patterns that largely overlap.
Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Purification&Purity :affinity purified by Protein A
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :KCTD7 Polyclonal Antibody detects endogenous levels of KCTD7 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :BTB/POZ domain containing protein KCTD7; EPM3; FLJ32069; Potassium channel tetramerisation domain containing 7; KCTD7_HUMAN.
Immunogen :KLH conjugated synthetic peptide derived from human KCTD7:112-180/289
Modification :Unmodification
