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LRP5L Polyclonal Antibody

货号: BS65694

价格：￥ ——

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS65694

Product Name :LRP5L Polyclonal Antibody

Swiss-Prot :A4QPB2

Host :Rabbit

Reactivity :Human,Mouse,Rat,Chicken,Sheep,

Applications :WB,

Application_all :WB=1:500-2000

Background :Members of the LDL receptor gene family, including LDLR (low density lipo-protein receptor), LRPs (low density lipoprotein related proteins), Megalin (also designated GP330), VLDLR (very low density lipoprotein receptor) and ApoER2, are characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. Of the known family members, LRP5 is most closely related to LRP1. However, LRP5 has a unique organization of EGF and LDLR repeats compared to other LDLR family members and likely represents a new category in this family. LRP is expressed in rat tibia, specifically in areas of the bone that are involved in remodeling. LRP5 is a Wnt coreceptor that binds to Axin and regulates the canonical Wnt signaling pathway. LRP5 affects bone mass accrual during growth. Mutations in LRP5 cause the autosomal recessive disorder osteoporosis-pseudoglioma syndrome (OPPG). LRP5L is a related protein that exists as two isoforms produced by alternative splicing.

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :affinity purified by Protein A

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :LRP5L Polyclonal Antibody detects endogenous levels of LRP5L protein.

BiowMW :28 kD

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Low-density lipoprotein receptor-related protein 5-like protein; LRP-5-like; LRP5L; GP330; LRP5L_HUMAN.

Immunogen :KLH conjugated synthetic peptide derived from human LRP5L

Conjugate :Unconjugated

Modification :Unmodification

Sample: U2os(Human) Cell Lysate at 30 ug 293T(Human) Cell Lysate at 30 ug Primary: Anti-LRP5L at 1/1000 dilution

Sample: U2OS(Human) Cell Lysate at 30 ug Primary: Anti- LRP5L at 1/1000 dilution