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BBS1 Polyclonal Antibody

货号: BS65686

价格：￥ ——

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS65686

Product Name :BBS1 Polyclonal Antibody

Swiss-Prot :Q8NFJ9

Host :Rabbit

Reactivity :Human,Mouse,Rat,Dog,Cow,Horse,Rabbit,Sheep,

Applications :WB,IHC-P,

Application_all :WB=1:500-2000 IHC-P=1:100-500

Background :The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane.

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :affinity purified by Protein A

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :BBS1 Polyclonal Antibody detects endogenous levels of BBS1 protein.

BiowMW :65 kD

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :AI451249; Bardet-Biedl syndrome 1; Bardet-Biedl syndrome 1 homolog; Bardet-Biedl syndrome 1 protein; BBS1; BBS1_HUMAN; BBS2-like protein 2; D19Ertd609e.

Immunogen :KLH conjugated synthetic peptide derived from human BBS5

Conjugate :Unconjugated

Modification :Unmodification

Sample: HepG2(Human) Cell Lysate at 30 ug U2os(Human) Cell Lysate at 30 ug Primary: Anti- BBS1 at 1/1000 dilution

Paraformaldehyde-fixed, paraffin embedded (mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (BBS1) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C