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Nova1 Polyclonal Antibody

货号: BS65682

价格：￥ ——

货期：现货（1-2个工作日）

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No. :BS65682

Product Name :Nova1 Polyclonal Antibody

Swiss-Prot :P51513

Host :Rabbit

Reactivity :Human,Mouse,Rat,Chicken,Cow,

Applications :WB,

Application_all :WB=1:500-2000

Background :Nova-1 and Nova-2 are members of a superfamily of protein regulators of RNA metabolism in neurons. Both are nuclear RNA binding proteins with K homology motifs, conserved protein sequences which bind to RNA (1,2). Nova proteins, normally sequestered in the central nervous system, are expressed by systemic tumors in patients with the autoimmune disorder paraneoplastic opsoclonus-myoclonus ataxia (POMA) (3,4). Nova-1 is expressed in the hindbrain and ventral spinal cord and Nova-2 is expressed in the neocortex and hippocampus (4). Nova-1 is necessary for regulating neuron-specific alternative splicing of the glycine receptor Alpha2 pre-mRNA (5).

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :affinity purified by Protein A

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Nova1 Polyclonal Antibody detects endogenous levels of Nova1 protein.

BiowMW :52 kD

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Neuro oncological ventral antigen 1; Neuro-oncological ventral antigen 1; NOVA 1; Nova-1; Nova1; NOVA1_HUMAN; Onconeural ventral antigen 1; Paraneoplastic Ri antigen; RNA binding protein Nova 1; RNA-binding protein Nova-1; Ventral neuron specific protein 1; Ventral neuron-specific protein 1.

Immunogen :KLH conjugated synthetic peptide derived from human Nova1

Conjugate :Unconjugated

Modification :Unmodification

Sample: Cerebrum (Mouse) Lysate at 40 ug Cerebrum (Rat) Lysate at 40 ug Primary: Anti-Nova1 at 1/1000 dilution

Sample: DU145(Human) Cell Lysate at 30 ug U87MG(Human) Cell Lysate at 30 ug Primary: Anti- Nova1 at 1/1000 dilution