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GRAF Polyclonal Antibody

货号: BS65676

价格：￥ ——

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS65676

Product Name :GRAF Polyclonal Antibody

Swiss-Prot :Q9UNA1

Host :Rabbit

Reactivity :Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Rabbit,Sheep,

Applications :WB,

Application_all :WB=1:500-2000

Background :Cellular signaling by G-proteins is down-regulated by GTPase-activating proteins (GAPs), which increase the rate of GTP hydroylsis. The GTPase regulator associated with focal adhesion kinase (GRAF) has GAP activity toward Rho A and Cdc42, but not Rac1. GRAF is ubiquitously expressed with high levels in heart and brain. Expression of GRAF causes clearing of stress fibers and formation of long actin based filopodial-like extensions. Fusion of MLL with GRAF, MLL/GRAF, is included in a rare genetic subgroup of acute myeloid leukemia (AML) cases.

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :affinity purified by Protein A

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :GRAF Polyclonal Antibody detects endogenous levels of GRAF protein.

BiowMW :38 kD

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :arhgap 26; ARHGAP26; FLJ42530; GRAF; GRAF1; GTPase regulator associated with focal adhesion kinase; GTPase regulator associated with focal adhesion kinase pp125(FAK); KIAA0621; oligophrenin 1 like protein; Oligophrenin-1-like protein; oligophrenin1like protein; OPHN1L; OPHN1L1; RHG26_HUMAN; Rho GTPase activating protein 26; Rho GTPase activating protein26; Rho GTPase-activating protein 26; Rho-type GTPase-activating protein 26.

Immunogen :KLH conjugated synthetic peptide derived from human GRAF1

Conjugate :Unconjugated

Modification :Unmodification

Sample: Cerebrum(Rat) Lysate at 40 ug Cerebrum(Mouse) Lysate at 40 ug Cerebellum(Rat) Lysate at 40 ug HepG2(Human) Cell Lysate at 30 ug Kidney(Rat) Lysate at 40 ug Kidney(Mouse) Lysate at 40 ug A549(Human) Cell Lysate at 30 ug A431(Human) Cell Lysate at 30 ug HL60(Human) Cell Lysate at 30 ug U937(Human) Cell Lysate at 30 ug Cerebellum(Mouse) Lysate at 40 ug Primary: Anti-GRAF at 1/1000 dilution