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MOBP Polyclonal Antibody

货号: BS65670

价格：￥ ——

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS65670

Product Name :MOBP Polyclonal Antibody

Swiss-Prot :Q13875

Host :Rabbit

Reactivity :Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep,

Applications :IHC-P,

Application_all :IHC-P=1:100-500

Background :The gene encoding MOBP a member of the central nervous system myelin-constituting proteins, maps to chromosome 3p22.2. MOBP has many splice variants that share a 68 amino acid N-terminal domain. MOBP-71, MOBP-81A, MOBP-99, and MOBP-169 are MOBP splice variants that contain exon 8b, which is similar to myelin basic protein (MBP) mRNA RTS, however MOBP-69, MOBP-81B, and MOBP-170 lack this exon. The splice variants that contain exon 8b are expressed in myelin, while those lacking exon 8b are retained in the oligodendrocyte soma. Exon 8b-containing variants are directed to sites of myelin sheath assembly by exon 8b, where they play a structural role in myelin formation. Splice variants lacking exon 8b likely play a cellular and/or regulatory role. MOBP is implicated in multiple sclerosis (MS), a human demyelinating disease, and in allergic encephalomyelitis in rodents.

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :affinity purified by Protein A

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :MOBP Polyclonal Antibody detects endogenous levels of MOBP protein.

BiowMW :21kD

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MGC87379; Myelin associated oligodendrocyte basic protein; MOBP_HUMAN.

Immunogen :KLH conjugated synthetic peptide derived from human MOBP

Conjugate :Unconjugated

Modification :Unmodification

Positive sample：Paraformaldehyde-fixed, paraffin embedded (mouse brian); Negative sample：Paraformaldehyde-fixed, paraffin embedded (rat liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MOBP) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C

Positive sample：Paraformaldehyde-fixed, paraffin embedded (rat brian); Negative sample：Paraformaldehyde-fixed, paraffin embedded (rat liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MOBP) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C