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mAChR M2 polyclonal antibody

货号: BS6566

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6566

Product Name :mAChR M2 polyclonal antibody

Swiss-Prot :P08172

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB IF

Application_all :WB 1:500 - 1:2000 IF 1:50 - 1:200

Background :The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels. The mAChRs transducer signals by coupling to G-proteins, which then modulate several downstream effector proteins and ion channels. Five mAChR subtypes have been identified, designated M1 to M5. The five receptor subtypes show distinct patterns of tissue distribution, as well as distinct pharmacological and functional properties.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :mAChR M2 polyclonal antibody detects endogenous levels of mAChR M2 protein.

BiowMW :~ 52 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CHRM2; Muscarinic acetylcholine receptor M2

Immunogen :Recombinant full length Human mAChR M2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of 293 cell line, using mAChR M2 antibody.

Acetylcholine Attenuates Hypoxia/ Reoxygenation-Induced Mitochondrial and Cytosolic ROS Formation in H9c2 Cells via M2 Acetylcholine Receptor

JournalCellular Physiology And Biochemistry

ApplicationWB

IF0

SpeciesRat

PMID23407103
Acetylcholine Inhibits Tumor Necrosis Factor α Activated Endoplasmic Reticulum Apoptotic Pathway via EGFR‐PI3K Signaling in Cardiomyocytes

JournalJournal Of Cellular Physiology

ApplicationWB

IF5.546

SpeciesRat

PMID25201632