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Integrin alpha 6 Polyclonal Antibody

货号: BS65611

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS65611

Product Name :Integrin alpha 6 Polyclonal Antibody

Swiss-Prot :P23229

Host :Rabbit

Reactivity :Human, (predicted: Mouse, Rat, Chicken, Cow, )

Applications :WB,

Application_all :WB=1:500-2000

Background :Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around twenty two different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell surface receptors, they bind ligands with very low affinity. Due to their weak individual binding, integrins need to cluster and bind in groups in order to effectively bind the ECM. Integrins bind many different ligands including laminin. Each integrin is made up of a large N terminal extracellular domain that binds the ECM ligand and a small C terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function. Integrin alpha 6 complexes are receptors for laminins, which are components of basement membranes. Integrin alpha 6 complexes may play an important role in embryogenesis.

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :affinity purified by Protein A

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Integrin alpha 6 Polyclonal Antibody detects endogenous levels of Integrin alpha 6 protein.

BiowMW :115 kD

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Integrin alpha-6; Alpha6p; VLA 6 alpha subunit; VLA 6; VLA-6; Integrin α6; CD49 antigen-like family member F; CD49f; Integrin alpha6B; Integrin, alpha 6; ITA6_HUMAN; ITGA6; ITGA6B; Processed integrin alpha-6.

Immunogen :KLH conjugated synthetic peptide derived from human Integrin alpha 6:1031-1130/1130 <Cytoplasmic>

Conjugate :Unconjugated

Modification :Unmodification

Sample: Lane 1: SW480 (Human) Cell Lysate at 30 ug Lane 2: A549 (Human) Cell Lysate at 30 ug Lane 3: Huvec (Human) Cell Lysate at 30 ug Lane 4: A431 (Human) Cell Lysate at 30 ug Primary: Anti-Integrin alpha 6 at 1/1000 dilution

Sample: A549 Cell (Human) Lysate at 40 ug Primary: Anti-Integrin alpha 6 at 1/300 dilution