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JNK1+JNK2+JNK3 Polyclonal Antibody

货号: BS65605

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS65605

Product Name :JNK1+JNK2+JNK3 Polyclonal Antibody

Swiss-Prot :Q61831

Host :Rabbit

Reactivity :Human, Mouse, Rat, (predicted: Dog, Pig, Cow, )

Applications :WB,IHC-P,

Application_all :WB=1:500-2000 IHC-P=1:100-500

Background :JNK1(MAPK8) is a member of the MAP kinase family. JNK1 is activated by threonine and tyrosine phosphorylation by either of two dual specificity kinases, MAP2K4 and MAP2K7. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53. JNK3 is a neuron-specific form of c-Jun N-terminal kinases. Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways of neuronal apoptosis. The JNK pathway is critically involved in diabetes and levels are abnormally elevated in obesity.

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :affinity purified by Protein A

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :JNK1+JNK2+JNK3 Polyclonal Antibody detects endogenous levels of JNK1+JNK2+JNK3 protein.

BiowMW :42-52 kD

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :JNK1 + JNK2 + JNK3; JNK1/2/3; JNK1+2+3; JNK1 + JNK2 + JNK3; MAPK10; c Jun N terminal kinase 1; c Jun N terminal kinase 2; c Jun N terminal kinase 3; JNK; JNK1; JNK2; JNK2ALPHA; JNK2BETA; JNK3; MAPK8; MAPK9; Mitogen activated protein kinase 10; Mitogen activated protein kinase 8; Mitogen activated protein kinase 9; SAPK(beta); Stress activated protein kinase JNK1; Stress activated protein kinase JNK2; Stress activated protein kinase JNK3; SAPK; p54a; JNK2A; JNK2B; PRKM9; JNK-55; SAPK1a; JNK2BETA; p54aSAPK; JNK2ALPHA.

Immunogen :KLH conjugated synthetic peptide derived from human JNK1/2/3:151-250/384

Conjugate :Unconjugated

Modification :Unmodification

Sample: Kidney (Mouse) Lysate at 40 ug Primary: Anti-JNK1+JNK2+JNK3 at 1/300 dilution

Sample: Cerebrum(Rat) Lysate at 40 ug Cerebrum(Mouse) Lysate at 40 ug Heart(Rat) Lysate at 40 ug Heart(Mouse) Lysate at 40 ug Cerebellum(Rat) Lysate at 40 ug Cerebellum(Mouse) Lysate at 40 ug Primary: Anti-JNK1+JNK2+JNK3 at 1/1000 dilution

Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (JNK1+JNK2+JNK3) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C,

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