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MCFD2 polyclonal antibody

货号: BS65593

价格：￥ ——

货期：现货（1-2个工作日）

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No. :BS65593

Product Name :MCFD2 polyclonal antibody

Swiss-Prot :Q8K5B2

Host :Rabbit

Reactivity :Mouse,Rat,

Applications :WB,

Application_all :WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

Background :This gene encodes a soluble luminal protein with two calmodulin-like EF-hand motifs at its C-terminus. This protein forms a complex with LAMN1 (lectin mannose binding protein 1; also known as ERGIC-53) that facilitates the transport of coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment (ERGIC). Mutations in this gene cause combined deficiency of FV and FVIII (F5F8D); a rare autosomal recessive bleeding disorder characterized by mild to moderate bleeding and coordinate reduction in plasma FV and FVIII levels. This protein has also been shown to maintain stem cell potential in adult central nervous system and is a marker for testicular germ cell tumors. The 3' UTR of this gene contains a transposon-like human repeat element named 'THE 1'. A processed RNA pseudogene of this gene is on chromosome 6p22.1. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jun 2010]

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :affinity purified by Protein A

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :MCFD2 polyclonal Antibody detects endogenous levels of MCFD2 protein.

BiowMW :~14kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :1810021C21Rik; DKFZp686G21263; F5F8D; LMAN1IP; MCFD 2; Mcfd2; MCFD2_MOUSE; Multiple coagulation factor deficiency protein 2; Neural stem cell derived neuronal survival protein; Neural stem cell-derived neuronal survival protein; SDNSF.

Immunogen :KLH conjugated synthetic peptide derived from mouse MCFD2:1-100/145

Conjugate :Unconjugated

Modification :Unmodification

Anti-MCFD2 at 1/1000 dilution