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CDK6 polyclonal antibody

货号: BS6559

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS6559

Product Name :CDK6 polyclonal antibody

Swiss-Prot :Q00534

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF/ICC

Application_all :WB: 1:500~1:2000 IHC: 1:50~1:200 IF/ICC: 1:50~1:200

Background :Cdk6 is known to associate with cyclins D1, D2 and D3 and to be involved with the G1/S transition of the cell cycle. Multiple inhibitors of Cdk6 have been identified, including p18 and p19. These inhibitors bind to both free and complexed Cdk6, and they inhibit the activity of the cyclin D-bound Cdk6.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CDK6 polyclonal antibody detects endogenous levels of CDK6 protein.

BiowMW :~ 37 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Cell Cycle Control G1 S Checkpoint,

Alternative Name :CDK 6; CDK6; CDK6; Cell division protein kinase 6; Crk 2; Crk2; Cyclin dependent kinase 6; Cyclin-dependent kinase 6; MGC59692; p40; PLSTIRE; Serine/threonine protein kinase PLSTIRE; Serine/threonine-protein kinase PLSTIRE; STQTL11

Immunogen :Recombinant full length protein of human CDK6.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of CDK6 expression in Jurkat (A), K562 (B) whole cell lysates.

Immunohistochemical analysis of CDK6 staining in human brain formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of CDK6 staining in K562 cells.

Anti-proliferative potential of Glucosamine in renal cancer cells via inducing cell cycle arrest at G0/G1 phase

JournalBMC Urology

ApplicationWB

IF1.592

SpeciesHuman

PMID28558682
MicroRNA-302b-3p Suppresses Cell Proliferation Through AKT Pathway by Targeting IGF-1R in Human Gastric Cancer

JournalCellular Physiology And Biochemistry

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IF0

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PMID28743112
KLK11 suppresses cellular proliferation via inhibition of Wnt/β-catenin signaling pathway in esophageal squamous cell carcinoma

JournalAmerican Journal of Cancer Research

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IF5.177

SpeciesHuman

PMID31720087
miR-34a-5p inhibits the malignant progression of KSHV-infected SH-SY5Y cells by targeting c-fos

JournalPeerJ

ApplicationWB,IHC

IF2.984

SpeciesHuman,Mouse

PMID35444864