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hydrogen exchanger 3 polyclonal antibody

货号: BS65548

价格：￥ ——

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS65548

Product Name :hydrogen exchanger 3 polyclonal antibody

Swiss-Prot :P48764

Host :Rabbit

Reactivity :Human,Mouse,Rat,Pig,Cow,Rabbit,Sheep,

Applications :WB,

Application_all :WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

Background :NHE-3 are integral membrane proteins that are expressed in most mammalian tissues, where they regulate intracellular pH and cell volume. NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions. While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics. NHE-3 localizes to the apical membrane of renal proximal tubules where it is responsible for most of the sodium transport and fluid reabsorption. NHE-3 translocates to internal pools where it mediates natriuresis when blood pressure increases abruptly. NHE-3 is also expressed in the stomach and functions to protect the mucosa by secreting protons that diffuse into the mucous cells.

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :affinity purified by Protein A

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :hydrogen exchanger 3 polyclonal Antibody detects endogenous levels of hydrogen exchanger 3 protein.

BiowMW :~80kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Na(+)/H(+) exchanger 3; NHE 3; NHE-3; NHE3; SL9A3_HUMAN; SLC9A 3; Sodium; Slc9a3; Sodium/hydrogen exchanger 3; Sodium/hydrogen exchanger, apical epithelial; Solute carrier family 9 (sodium/hydrogen exchanger), isoform 3; Solute carrier family 9 (sodium/hydrogen exchanger), member 3; Solute carrier family 9 member 3; MGC126718; MGC126720.

Immunogen :KLH conjugated synthetic peptide derived from human hydrogen exchanger 3 :581-680/834 <Cytoplasmic>

Conjugate :Unconjugated

Modification :Unmodification

Anti-hydrogen exchanger 3 at 1/1000 dilution