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Cyclin D1 monoclonal Antibody

货号: BS65502

价格：￥ 1860

货期：现货（1-2个工作日）

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No. :BS65502

Product Name :Cyclin D1 monoclonal Antibody

Swiss-Prot :P25322

Host :Rabbit

Reactivity :Human

Applications :WB,IHC-P

Application_all :WB=1:500-2000 IHC-P=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

Background :The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :affinity purified by Protein A

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Cyclin D1 monoclonal Antibody detects endogenous levels of Cyclin D1 protein.

BiowMW :~34 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CyclinD1; Cyclin-D1; B cell ccl/lymphoma 1; B cell leukemia 1; B-cell CLL/lymphoma 1; B-cell leukemia 1; B-cell lymphoma 1 protein; BCL-1; BCL1; BCL1 oncogene; CCND 1; CCND1; CCND1 protein; CCND1/FSTL3 fusion gene, included; CCND1/IGHG1 fusion gene; CCND1/IGHG1 fusion gene, included; CCND1/IGLC1 fusion gene, included; CCND1/PTH fusion gene, included; Parathyroid adenomatosis 1; PRAD1; FSTL3; CCND1_HUMAN; AI327039; B cell lymphoma 1 protein; BCL 1; BCL-1; BCL-1 oncogene; BCL1 oncogene; CCND1/FSTL3 fusion gene, included; cD1; Cyl 1; D11S287E; G1/S specific cyclin D1; G1/S-specific cyclin-D1.

Immunogen :Recombinant human Cyclin D1 protein, around C-terminal 150aa:

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Cyclin D1 monoclonal antibody at 1:1000 dilution.

Immunohistochemistry of paraffin-embedded human tonsil damage using Cyclin D1 monoclonal antibody at dilution of 1:200.

A novel role of ribonuclease inhibitor in regulation of epithelial-to-mesenchymal transition and ILK signaling pathway in bladder cancer cells

JournalCell And Tissue Research

ApplicationWB

IF5.249

SpeciesHuman,Mouse

PMID23703635
Effect of nerve growth factor on the proliferation in newborn bovine testicular Sertoli cells

JournalReproduction

ApplicationWB

IF3.206

SpeciesBovine

PMID32567558
Enhancement of osteogenesis of rabbit bone marrow derived mesenchymal stem cells by transfection of human BMP‑2 and EGFP recombinant adenovirus via Wnt signaling pathway

JournalExperimental and Therapeutic Medicine

ApplicationWB

IF1.785

SpeciesRabbit

PMID30402148