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ANKLE2 Polyclonal Antibody

货号: BS65473

价格：￥ ——

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

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No. :BS65473

Product Name :ANKLE2 Polyclonal Antibody

Swiss-Prot :Q86XL3

Host :Rabbit

Reactivity :Human,Mouse,Rat,Cow,Horse,Rabbit,Sheep,

Applications :WB,

Application_all :WB=1:500-2000

Background :Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKLE2 (ankyrin repeat and LEM domain containing 2), also known as LEMD7, is a 938 amino acid single-pass membrane protein containing an ANK repeat and a LEM domain. Exsiting as two isoforms produced by alternative splicing events, the gene encoding ANKLE2 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :affinity purified by Protein A

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ANKLE2 Polyclonal Antibody detects endogenous levels of ANKLE2 protein.

BiowMW :117 kD

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ANKL2_HUMAN; ANKLE 2; ANKLE2; ankyrin repeat and LEM domain containing 2; Ankyrin repeat and LEM domain-containing protein 2; LEM domain containing 7; LEMD 7; LEMD7.

Immunogen :KLH conjugated synthetic peptide derived from human ANKLE2:251-350/938

Conjugate :Unconjugated

Modification :Unmodification

Primary: Anti-ANKLE2 at 1/1000 dilution