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ILK (phospho Ser246) Polyclonal Antibody

货号: BS65380

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :BS65380

Product Name :ILK (phospho Ser246) Polyclonal Antibody

Swiss-Prot :Q13418

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :IHC-p,IF(paraffin section),ELISA

Application_all :Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Background :integrin linked kinase(ILK) Homo sapiens This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Phospho-ILK (S246) Polyclonal Antibody detects endogenous levels of ILK protein only when phosphorylated at S246.

BiowMW :/

Note :For research use only, not for use in diagnostic procedure.

Pathway :Contribution of ECM and Cytoskeletal Factors to EMT,

Alternative Name :ILK; ILK1; ILK2; Integrin-linked protein kinase; 59 kDa serine/threonine-protein kinase; ILK-1; ILK-2; p59ILK

Immunogen :The antiserum was produced against synthesized peptide derived from human ILK around the phosphorylation site of Ser246. AA range:212-261

Conjugate :Unconjugated

Modification :Phosphorylation

Immunohistochemistry analysis of paraffin-embedded human brain, using ILK (Phospho-Ser246) Antibody. The picture on the right is blocked with the phospho peptide.