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MAPKAPK-2 (phospho Ser272) Polyclonal Antibody

货号: BS65376

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :BS65376

Product Name :MAPKAPK-2 (phospho Ser272) Polyclonal Antibody

Swiss-Prot :P49137

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-p,IF(paraffin section),ELISA

Application_all :Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Background :mitogen-activated protein kinase-activated protein kinase 2(MAPKAPK2) Homo sapiens This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Phospho-MAPKAPK-2 (S272) Polyclonal Antibody detects endogenous levels of MAPKAPK-2 protein only when phosphorylated at S272.

BiowMW :~45-52 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Regulation of Microtubule Dynamics,Signaling Pathways Activating p38 MAP Kinase

Alternative Name :MAPKAPK2; MAP kinase-activated protein kinase 2; MAPK-activated protein kinase 2; MAPKAP kinase 2; MAPKAP-K2; MAPKAPK-2; MK-2; MK2

Immunogen :The antiserum was produced against synthesized peptide derived from human MAPKAPK2 around the phosphorylation site of Ser272. AA range:238-287

Conjugate :Unconjugated

Modification :Phosphorylation

Western blot analysis of lysates from RAW264.7 cells treated with UV 15', using MAPKAPK2 (Phospho-Ser272) Antibody. The lane on the right is blocked with the phospho peptide.

Immunohistochemistry analysis of paraffin-embedded human brain, using MAPKAPK2 (Phospho-Ser272) Antibody. The picture on the right is blocked with the phospho peptide.