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HSD3B7 polyclonal antibody

货号: BS65304

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS65304

Product Name :HSD3B7 polyclonal antibody

Swiss-Prot :Q9H2F3

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,ELISA

Application_all :Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Background :hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7(HSD3B7) Homo sapiens This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :3β-HSD7 Polyclonal Antibody detects endogenous levels of 3β-HSD7 protein.

BiowMW :~ 41 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HSD3B7; 3 beta-hydroxysteroid dehydrogenase type 7; 3 beta-hydroxysteroid dehydrogenase type VII; 3-beta-HSD VII; 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase; C(27) 3-beta-HSD; Cholest-5-ene-3-beta; 7-alpha-diol 3-beta-dehydrogenase

Immunogen :The antiserum was produced against synthesized peptide derived from human HSD3B7. AA range:121-170

Conjugate :Unconjugated

Modification :Unmodification

Western Blot analysis of various cells using 3β-HSD7 Polyclonal Antibody diluted at 1：1000

Western Blot analysis of COLO205 cells using 3β-HSD7 Polyclonal Antibody diluted at 1：1000

Western blot analysis of lysates from HeLa, MCF-7, and COLO cells, using HSD3B7 Antibody. The lane on the right is blocked with the synthesized peptide.

Western blot analysis of the lysates from Jurkat cells using HSD3B7 antibody.