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KCNA1 polyclonal antibody

货号: BS65292

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS65292

Product Name :KCNA1 polyclonal antibody

Swiss-Prot :Q09470

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,ELISA

Application_all :Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Background :potassium voltage-gated channel subfamily A member 1(KCNA1) Homo sapiens This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK). [provided by RefSeq, Jul 2008]

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :KV1.1 Polyclonal Antibody detects endogenous levels of KV1.1 protein.

BiowMW :~ 57 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :KCNA1; Potassium voltage-gated channel subfamily A member 1; Voltage-gated K(+) channel HuKI; Voltage-gated potassium channel HBK1; Voltage-gated potassium channel subunit Kv1.1

Immunogen :The antiserum was produced against synthesized peptide derived from human KCNA1. AA range:256-305

Conjugate :Unconjugated

Modification :Unmodification

Western Blot analysis of HeLa cells using KV1.1 Polyclonal Antibody diluted at 1：2000

Western blot analysis of lysates from HUVEC, MCF-7, and HeLa cells, using KCNA1 Antibody. The lane on the right is blocked with the synthesized peptide.

Western blot analysis of the lysates from HepG2 cells using KCNA1 antibody.