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RAB11FIP2 polyclonal antibody

货号: BS65265

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS65265

Product Name :RAB11FIP2 polyclonal antibody

Swiss-Prot :Q7L804

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB,ELISA

Application_all :Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Background :function:A Rab11 effector protein acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Binds preferentially to phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA).,similarity:Contains 1 C2 domain.,subcellular location:Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane.,subunit:Homooligomerizes in a Rab11-independent manner. Forms an heterooligomeric complex with RAB11FIP4. Interacts with AP2A1, MYO5B, RAB11A, RAB11B, RAB25 and REPS1. Interacts with RAB11A/RAB11B that has been activated by GTP binding.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Rab11-FIP2 Polyclonal Antibody detects endogenous levels of Rab11-FIP2 protein.

BiowMW :~ 58 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RAB11FIP2; KIAA0941; Rab11 family-interacting protein 2; Rab11-FIP2; NRip11

Immunogen :The antiserum was produced against synthesized peptide derived from human RAB11FIP2. AA range:340-389

Conjugate :Unconjugated

Modification :Unmodification

Western Blot analysis of MCF-7 cells using Rab11-FIP2 Polyclonal Antibody

Western blot analysis of lysates from MCF-7, HUVEC, A549, and COLO cells, using RAB11FIP2 Antibody. The lane on the right is blocked with the synthesized peptide.

Western blot analysis of the lysates from HepG2 cells using RAB11FIP2 antibody.