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CEP57 polyclonal antibody

货号: BS65258

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS65258

Product Name :CEP57 polyclonal antibody

Swiss-Prot :Q86XR8

Host :Rabbit

Reactivity :Human

Applications :WB,ELISA

Application_all :Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Background :centrosomal protein 57(CEP57) Homo sapiens This gene encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization, and the C-terminal half is required for nucleating, bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2), sorting nexin 6, Ran-binding protein M and the kinesins KIF3A and KIF3B, and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining correct chromosomal number during cell division. Mutations in this gene cause mosaic variegated aneuploidy syndrome, a rare autosomal recessive disorder. Multiple

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CEP57 Polyclonal Antibody detects endogenous levels of CEP57 protein.

BiowMW :~ 50 kDa

Note :For

Alternative Name :CEP57; KIAA0092; TSP57; Centrosomal protein of 57 kDa; Cep57; FGF2-interacting protein; Testis-specific protein 57; Translokin

Immunogen :The antiserum was produced against synthesized peptide derived from human CEP57. AA range:241-290

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of lysates from COLO and LOVO cells, using CEP57 Antibody. The lane on the right is blocked with the synthesized peptide.

免疫沉淀（IP）