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Caldesmon(Ab-759)polyclonal antibody

货号: BS65240

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :BS65240

Product Name :Caldesmon(Ab-759)polyclonal antibody

Swiss-Prot :Q05682

Host :Mouse/IgG2b, Kappa

Reactivity :Human

Applications :IHC-p,IF(paraffin section)

Application_all :IHC-p 1:100-500，WB 1:500-2000

Background :caldesmon 1(CALD1) Homo sapiens This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :This antibody detects endogenous levels of human Caldesmon. Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was highly recommended as antigen repair method in paraffin section

BiowMW :/

Note :For

Immunogen :Synthesized peptide derived from human Caldesmon

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemical analysis of paraffin-embedded Liomyoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).

Immunohistochemical analysis of paraffin-embedded Colon. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).

Western blot analysis of CaldesmonAntibody at 1:1000 dilution.