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GLI-3 polyclonal antibody

货号: BS65224

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS65224

Product Name :GLI-3 polyclonal antibody

Swiss-Prot :P10071

Host :Rabbit

Reactivity :Human

Applications :IHC-p,IF/ICC,ELISA

Application_all :Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Background :GLI family zinc finger 3(GLI3) Homo sapiens This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008],

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :GLI-3 Polyclonal Antibody detects endogenous levels of GLI-3 protein.

Note :For

Pathway :Hedgehog Signaling,

Alternative Name :GLI3; Transcriptional activator GLI3; GLI3 form of 190 kDa; GLI3-190; GLI3 full length protein; GLI3FL

Immunogen :The antiserum was produced against synthesized peptide derived from human GLI-3. AA range:11-60

Conjugate :Unconjugated

Modification :Unmodification

Immunofluorescence analysis of HepG2 cells, using GLI-3 Antibody. The picture on the right is blocked with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using GLI-3 Antibody. The picture on the right is blocked with the synthesized peptide.