产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

IL1 beta polyclonal antibody

货号: BS65005

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS65005

Product Name :IL1 beta polyclonal antibody

Swiss-Prot :P01584

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IL1 beta polyclonal antibody detects endogenous levels of IL1 beta protein.

BiowMW :~ 17,35kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Immune Cell Signaling,Inflammasonme Signaling,Necrotic Cell Death,

Alternative Name :IL-1;IL1-BETA;IL1F2;IL1 beta;IL1B

Immunogen :Synthetic peptide, corresponding to Human IL1 beta.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of IL-1 beta expression in Raw264.7 (A), mouse spleen (B), rat spleen (C), rat thymus (D), mouse thymus (E), Jurkat (F), THP1 (G) whole cell lysates.

Immunohistochemical analysis of IL-1 beta staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system.

mRNA and miRNA expression profiles reveal the potential roles of RLRs signaling pathway and mitophagy in duck hepatitis A virus type 1 infection

JournalPOULTRY SCIENCE

ApplicationWB

IF4.4

SpeciesDuck

PMID38810565