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Lamin A/C (Phospho-S392) polyclonal antibody

货号: BS65001

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :BS65001

Product Name :Lamin A/C (Phospho-S392) polyclonal antibody

Swiss-Prot :P02545

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB:1:500~1:1000 IHC:1:50~1:200 IF:1:50~1:200

Background :Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics.Prelamin-A/C can accelerate smooth muscle cell senescence. It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells (VSMCs), leading to mitotic failure, genomic instability, and premature senescence.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Lamin A/C (Phospho-S392) polyclonal antibody detects endogenous levels of Lamin A/C protein only when phosphorylated at Ser392.

BiowMW :~ 74, 65 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Prelamin-A/C; Lamin-A/C; Lamin A/C; LaminA/C; 70 kDa lamin; Renal carcinoma antigen NY-REN-32; LMNA; LMN1; Lamin A; LaminA; Lamin-A; Lamin C; LaminC; Lamin-C

Immunogen :Synthetic phosphopeptide derived from human Lamin A/C around the phosphorylation site of Serine 392.

Conjugate :Unconjugated

Modification :Phosphorylation

Western blot (WB) analysis of Lamin A/C (Phospho-S392) polyclonal antibody at 1:500 dilution LaneA:DLD whole cell lysate LaneB:The Kidney tissue lysate of Mouse LaneC:The Lung tissue lysate of Rat